Dr. Kizzmekia S. Corbett
4 March 2021
The Biomedical Research Center (BRC) of Qatar University hosted Dr. Kissmekia Corbett from the United States on 4/3/2021 to present a talk about COVID-19 mRNA vaccine development. Dr. Corbett is a senior research fellow at the Vaccine Research Center (VRC) of the National Institute of Health (NIH) and has led the collaboration between her institute (NIH) and Moderna to develop and evaluate the Moderna mRNA vaccine in preclinical and clinical trials. She works under the direct supervision of Dr. Barney Graham and Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases (NIAID) of NIH. She presented the different stages of vaccine development, illustrating with scientific data the utilized approaches to make the candidate vaccine available for phase I clinical trial 66 days after the emergence of the pandemic. Relying on former knowledge from MERS vaccine development, the Viral pathogenesis lab at VRC-NIH demonstrated the ability of mRNA vaccine to induce potent antibody response in preclinical settings (mice and monkeys), before the vaccine was tested in phase 1-3 human trials. Answering some questions, the speaker recommended the vaccination of pregnant and nursing mothers, noting that phase III clinical trial is undergoing in this regard. The seminar was moderated by Dr. Hadi Yassine from the Biomedical Research Center, who participated in coronavirus vaccine development at NIH before joining Qatar University.